Everything about Melphalan totally explained
Melphalan hydrochloride (trade name
Alkeran) is a
chemotherapy drug belonging to the class of
nitrogen mustard alkylating agents. It is used primarily to treat
multiple myeloma and
ovarian cancer, and occasionally
malignant melanoma. Otherwise known as L-Phenylalanine Mustard, or L-PAM, melphalan is a
phenylalanine derivative of
mechlorethamine. The agent was first investigated as a possible drug for use in melanoma. It didn't work, but was found to be of use in myeloma.
Administration
Oral or intravenous; dosing varies by purpose and route of administration as well as patient weight.
Side effects
Common side effects include:
Less common side effects include:
Severe allergic reactions
Scarring of lung tissue (usually only with prolonged use)
Hair loss
Rash
Itching
Further Information
Get more info on 'Melphalan'.
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